IS FlowMap Computer Program May Help Neurointerventionists Gauge Blood Flow During Aneurysm Treatment


February 3, 2015—A preliminary study of the use of a quantitative analysis of flow diverter-induced blood flow reduction in brain aneurysm treatment was presented at ISET 2015: the 27th annual International Symposium on Endovascular Therapy in Hollywood, Florida. According to the ISET press release, the study’s findings suggest that a new computer program may allow interventionists to assess blood flow as they are using flow-diverter devices to treat life-threatening aneurysms.

As summarized in the ISET announcement, the Intracranial Stent Flow Mapping computer program—IS FlowMap—takes advantage of the standard digital subtraction angiography (DSA) imaging taken during the procedure. The program analyzes the standard images, compares the difference in blood flow image to image, and calculates the changes within seconds, providing that information to the doctor during treatment. If blood flow is not optimal, the doctor may choose to use a different treatment, such as placing coils in the aneurysm.

In the study, 13 patients were treated, and the average reduction in blood flow entering the aneurysm was 48%. The flow diverter healed the aneurysm in 11 (85%) of the patients. The study was conducted by neuroradiologist Gary Duckwiler, MD, and scientists Aichi Chien, PhD, and Dominique Zosso, PhD, of the University of California, Los Angeles.

Dr. Chien, who is Assistant Professor of Interventional Neuroradiology at the UCLA David Geffen School of Medicine, commented in the ISET press release, “Until now, there was no safe way to measure the blood flow in real time, during the procedure, including flow reduction to the aneurysm and flow to the rest of the brain. Because the program quantifies blood flow automatically, doctors do not need to stop the procedure to get this information, which helps them make the best decisions during the procedure.”  

She concluded, “There are many advances in devices to treat patients with aneurysms and other vascular disease, but the technology to see the effects of those devices is very limited. The IS FlowMap provides a simple way to analyze the treatment without any additional procedures or risk. We’ll be able to use this information moving forward to compare treatment and determine what amount of blood flow change is optimal.”


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