Study Evaluates Medtronic's Solitaire 4- X 40-mm Stent Retriever for Stroke Treatment


December 22, 2017—A single-center evaluation of the safety and efficacy of the long Solitaire 2 flow restoration (FR) 4- X 40-mm stent retriever (Medtronic) for large vessel occlusion (LVO) in stroke patients was published by Felix Zibold, MD, et al in CardioVascular and Interventional Radiology (2018;41:49–54).

The investigators conducted a retrospective analysis of all patients treated for acute ischemic LVO stroke with the Solitaire 2 FR device between May and October 2016 at Inselspital, University of Bern in Bern, Switzerland.

As summarized in CardioVascular and Interventional Radiology, patient-specific data were documented at baseline and discharge. Reperfusion was graded with the thrombolysis in cerebral infarction (TICI) classification. Postinterventional angiograms and follow-up cross-sectional imaging were used to evaluate complications.

The investigators reported that TICI 2b/3 recanalization was achieved in 20 of 23 (87%) patients, including 17 patients with the first retriever pass. National Institutes of Health Stroke Scale improved from a mean score at presentation of 16 (range, 4–36) to 11 (range, 0–41) at discharge. Mean modified Rankin Scale score was 3 (range, 0–6) both at discharge and 90-days posttreatment. No infarcts in other territories were observed. One patient showed a (reversible) vasospasm in the postinterventional angiogram and another patient had a small contrast extravasation in follow-up imaging.

From these findings, the investigators concluded that the Solitaire 2 FR 4- X 40-mm stent retriever is a safe and effective device for LVO acute ischemic stroke with a high recanalization rate, a low peri- and postinterventional complication rate, and a good clinical outcome. Despite potentially higher friction and shearing forces, no increased incidence of visible damage to the vessel wall was observed, noted the investigators in CardioVascular and Interventional Radiology.


Contact Info

For advertising rates and opportunities, contact:
Craig McChesney

Stephen Hoerst

Charles Philip

About Endovascular Today

Endovascular Today is a publication dedicated to bringing you comprehensive coverage of all the latest technology, techniques, and developments in the endovascular field. Our Editorial Advisory Board is composed of the top endovascular specialists, including interventional cardiologists, interventional radiologists, vascular surgeons, neurologists, and vascular medicine practitioners, and our publication is read by an audience of more than 22,000 members of the endovascular community.