Advertisement

September 15, 2015

Aortic Neck Enlargement Compared After EVAR With Balloon-Expandable Versus Self-Expanding Endografts

September 16, 2015—In the Journal of Vascular Surgery (JVS), Janis Savlovskis, MD, et al published findings from a study that evaluated changes in aortic neck diameter after endovascular aneurysm repair (EVAR) using a balloon-expandable stent (BES) endograft compared with a commercially available self-expanding stent (SES) endograft (2015;62:541–549).

The investigators hypothesized that forces applied to the aortic neck by SES endografts may induce aortic neck enlargement over time and that such enlargement may not occur in patients treated with a device that does not use a proximal SES.

The study showed that EVAR using SES endografts resulted in progressive infrarenal aortic neck enlargement, whereas EVAR using BES endografts resulted in no neck enlargement over time. These data suggest that infrarenal neck enlargement after EVAR with SES endografts is likely related to the force exerted by SES elements rather than disease progression in the infrarenal neck, concluded the investigators in JVS.

As summarized in JVS, the study was a retrospective, quantitative, CT image analysis of patients treated with a BES endograft (n = 49; Nellix, Endologix, Inc.) or an SES endograft (n = 56; Endurant II, Medtronic plc) from 2008 to 2010. Patients with preimplant, postimplant, and at least 1-year serial CT scans underwent quantitative morphometric assessment by two independent vascular radiologists blinded to the outcome results. Changes in the infrarenal neck over time were compared with the suprarenal aorta for each patient.

Follow-up extended to 4.8 years for the BES and to 4.6 years for the SES, with no significant difference in median follow-up time (34 months for the BES and 24 months for the SES). There were no differences in preimplant neck diameter (25.2 ± 0.9 mm vs 25.7 ± 1.1 mm) or length (27.7 ± 3.7 mm vs 23.6 ± 3.7 mm) between the BES and SES at baseline.

After implantation, neck diameter increased by 1.1 ± 0.5 mm in BES patients and 2.6 ± 0.5 mm in SES patients compared with the preoperative diameter. At 3 years, neck diameter increased by 0.5 ± 0.9 mm in BES patients and by 3.8 ± 1 mm in SES patients compared with the first postoperative CT scan. The annual postimplant rate of increase in the infrarenal neck diameter was fivefold greater in SES patients (1.1 ± 0.1 mm/y) than in BES patients (0.22 ± 0.04 mm/y). There were no significant differences in the diameter of the suprarenal aorta at baseline or at 3 years and no differences in the annual rate of change in suprarenal aortic diameter between the BES and SES endografts, reported the investigators in JVS.

Advertisement


September 16, 2015

Ballooning Before Versus After CAS Compared for Effect on the Rate of Stroke and Death

September 16, 2015

Ballooning Before Versus After CAS Compared for Effect on the Rate of Stroke and Death