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August 7, 2020

Endovascular Treatment of Vein of Galen Aneurysmal Malformation Studied in Neonatal Patients

August 7, 2020—A new study showed that endovascular treatment of vein of Galen aneurysmal malformation (VGAM) in neonatal patients with severe pulmonary hypertension can improve chances of survival.

The Society of NeuroInterventional Surgery (SNIS) announced that the study, Outcomes of Endovascular Treatment of Vein of Galen Aneurysmal Malformation in Neonates, was presented at the SNIS 17th annual meeting held virtually August 4-7, 2020. The presentation abstract is available online in the SNIS meeting supplement to Journal of NeuroInterventional Surgery.

The investigators evaluated data from 52 surgery patients with VGAMs at the Meshalkin National Medical Research Center in Novosibirsk, Russia. Eleven of the patients were younger than 10 days old when surgery was performed. Before surgery, all patients underwent cardiac ultrasonography to measure pulmonary artery pressure and neurosonography to measure the linear blood flow velocity in the vein of Galen and afferent vessels. All patients had pronounced pulmonary hypertension.

Kirill Orlov, MD, lead investigator of the study, commented in the SNIS press release, “This technique reduces the severity of pulmonary hypertension, thus lowering the risk for developing critical heart failure or multiple organ failure, and allows babies to cross the critical line on their way to survival. These findings clearly indicate a new feasible treatment option for VGAM, marking a promising advancement of treatment in a case where there have been few paths forward to date.”

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