November 12, 2020
First Procedures Conducted With Transit Scientific’s XO Score Angioplasty System to Dilate Calcified and Fibrotic Vessels
November 12, 2020—Transit Scientific announced the first procedures using the company’s XO Score to dilate multiple challenging fibrotic and calcific lesions in hemodialysis patients with stenotic and occluded fistulas. The XO Score technology allows interventionalists to convert basic angioplasty balloons in the hospital’s existing inventory into sophisticated scoring, cutting, and infusion/delivery devices.
During an XO Score procedure, clinicians insert a basic angioplasty balloon into the ultra-thin XO Score sheath and advance the combined balloon and XO Sheath to the stenosis. When the balloon is inflated, up to 22 evenly spaced XO Score struts expand with the balloon and rotate 90º to score and cut the narrowed vessel. When the balloon is deflated, the struts rotate 90º back to an atraumatic position to assist balloon rewrap and removal.
In June, the company announced FDA clearance of the XO Score percutaneous transluminal angioplasty (PTA) scoring sheath platform to dilate stenotic material in iliac, iliofemoral, popliteal, infrapopliteal, and renal artery disease plus synthetic and/or native arteriovenous hemodialysis fistula.
Richard Saxon, MD, of the SDI Medical Group, performed the first procedure using XO Score at Tri-City Medical Center in Oceanside, California. Treatment of all the lesions proved successful, reported the company.
“The XO device performed well and demonstrated effective lesion dilatation at low pressures with a variety of our standard angioplasty balloons,” commented Dr. Saxon in Transit Scientific’s press release. “The rotating scoring struts appeared to be effective against a mix of fibrous and calcified lesions, which tend to be highly resistant to plain old angioplasty.”
Dr. Saxon continued, “One of the procedures required five separate inflations at various points along the native fistula and outflow vein, all of which were accomplished using the same XO Score device. The ability to achieve a more predictable result at a lower and potentially safer pressure in resistant lesions could prove important in achieving the best possible PTA outcomes and thereby help in fistula maintenance. The fact that you can take quick angiograms through the XO Score and around the PTA balloon was a nice additional feature.”