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February 28, 2019

Small Comparative Study Finds Patients Prefer Transradial Access Over Transfemoral Access

February 28, 2019—A recently published study found that patients favored transradial access (TRA) over transfemoral access (TFA) after experiencing both during the research period (22 [73.3%] vs 4 [13.3%] patients). Additionally, four (13.3%) of the 30 patients indicated that they did not have an access site preference. The study was published by Lisa B. Liu, BA, et al in Journal of Vascular and Interventional Radiology (JVIR; 2019;30:414–420).

According to the researchers in JVIR, the single-center study randomized patients with hepatocellular carcinoma undergoing mapping and transarterial radioembolization based on which access type they experienced first. After each access experience, patients were surveyed to assess pain and quality of life (QOL). Access site preference data were collected after the completion of both procedures, reported the study investigators.

Patient reporting of bruising was similar between TRA and TFA (14 [46.7%] vs 17 [53.3%] patients, respectively). Pain scores were significantly lower for TRA than TFA at all three collection points: overall during the procedure (2 vs 2.9; P = .0046), at the access site during the procedure (2 vs 3; P = .0004), and in the recovery room (2.1 vs 2.9; P = .0357). Investigators noted that pain score after discharge did not significantly differ between TRA and TFA (1.4 vs 1.5; P = .4235).

Other endpoints including QOL scores, fluoroscopy time, air kerma, dose-area product, and procedure time for mapping or radioembolization did not show statistically significant differences between the procedures. However, investigators reported that TRA had significantly shorter recovery times compared to TFA for radioembolization (108 vs 153 minutes; P = .0193).

The researchers concluded that when undergoing TRA, patients experienced less periprocedural pain and shorter recovery times without significant differences in radiation exposure or procedure length.

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