July 1, 2020
Study Published of Biomodex Patient-Specific Brain Aneurysm Models for Preprocedural Rehearsals
July 1, 2020—Biomodex announced the results of the first clinical study of the Biomodex Evias three-dimensional (3D)–printed models to plan aneurysm treatment using endovascular robotics and novel flow diverter devices. The company’s 3D-printed solutions were developed for patient-specific rehearsal and physician training.
Vitor Nagai Yamaki, MD, et al published the study online ahead of print in Journal of NeuroInterventional Surgery.
According to the company, the findings demonstrate how using the 3D-printed aneurysm models for preprocedural rehearsal allows physicians to rehearse for procedures more accurately and reliably.
The study was composed of eight patients with brain aneurysms who were scheduled for treatment using new devices or techniques. Two cases included simulation of stent-assisted coiling treatments using the assistance of a robotic arm (Corindus Vascular Robotics), and six included rehearsal for first-time use of new-generation flow-diverter stents, including the Silk Vista Baby (Balt) and Surpass Evolve (Stryker).
All rehearsals and procedures were performed by Vitor Mendes Pereira, MD, a neurosurgeon and neuroradiologist at Toronto Western Hospital in Toronto, Ontario. Dr. Pereira commented in the company’s announcement, “This technology has the potential to increase operator confidence and improve patient outcomes, particularly in first in-human experiences using new devices and robotics. The rehearsals were instrumental in our recent successful completion of the world’s first in-human robotic-assisted neurovascular intervention.” Dr. Pereira is senior investigator of the study and lead scientist of the RADIS lab research team.
The company noted that the study demonstrated how various procedural challenges were successfully replicated during patient treatment. The RADIS lab’s clinical research technologist and lead coinvestigator of the study, Nicole Cancelliere, MRT(R), found the models to be a reliable and accurate reproduction of the aneurysm features and the parent vessel anatomy. She stated in the press release, “The rehearsals allowed the operator to address issues, such as device sizing, and practice challenging maneuvers, such as how to open flow diverter stents.”
Biomodex’s 3D training models are created based on each patient’s unique CTA scans and printed using a Stratasys J750 digital anatomy 3D printer. Biomodex Invivotech material was used to simulate the biomechanics of the aneurysm and the surrounding tissue.
The models are made with various flexible photopolymers which, unlike single-material models like silicone, allow control of the pliability of the target area, providing critical tactile feedback. The models are connected to the Evias station, which includes a hydraulic system to replicate blood flow.