November 6, 2019
Treatment of Lateral Subdermic Plexus Insufficiency Evaluated for Restless Leg Syndrome
November 6, 2019—VIVA Physicians announced that Swar Shah, MD, presented findings from an investigation of the etiologies of restless leg syndrome (RLS) and nighttime leg cramping in a late-breaking clinical trial session at VIVA 2019, the Vascular InterVentional Advances meeting held November 4–7 in Las Vegas, Nevada.
According to Dr. Shah, physicians have noticed over the years that many patients with chronic superficial venous insufficiency/varicose veins have had presenting symptoms of RLS and nighttime leg cramping. Many of these patients also presented with abnormal reflux of the lateral subdermic venous plexus (LSP) and superficial veins on the lateral thigh and calf typically not evaluated in most settings.
It was hypothesized that there is an association between these leg symptoms and the poorly understood LSP.
As summarized in the VIVA announcement, investigators evaluated a total of 510 patients for a correlation between RLS/nighttime leg cramping with reflux in the LSP. Dr. Shah reported that in patients with either symptom, 83% and 89%, respectively, had an abnormal LSP on ultrasound. Of patients with both symptoms, 91% had an abnormal LSP on ultrasound.
A total of 242 symptomatic patients underwent ultrasound-guided foam sclerotherapy of the LSP, and up to 92% were symptom-free at 1 year.
The LSP appears to play a key role in RLS and nighttime cramping and should be added to the comprehensive venous ultrasound, especially for patients presenting with these symptoms; furthermore, treatment for this is simple, cheap, and effective and can be life-changing for many of these patients, concluded Dr. Shah at VIVA 2019.