Introduction

By Brent Keeling, MD, and Richard Channick, MD

COVID-19 and VTE: What We Know and What We Don’t Know

A review of what is currently known about the role of inflammation, markers of disease in coagulation studies, pathologic and clinical evidence of thrombosis, and the approach to anticoagulation of COVID-positive hospitalized patients.

By Oren A. Friedman, MD; Eugene Yuriditsky, MD; and James Horowitz, MD, FACC

The PERT Consortium® COVID-19 PE Registry: Introduction and Implementation

A discussion of the goals of the registry and what types of data are being collected and reported.

By Rachel P. Rosovsky, MD, MPH; George A. Davis, PharmD, BCPS; Robert Lookstein, MD, MHCDL, FSIR, FAHA, FSVM; and Kenneth Rosenfield, MD, MHCDS, FACC, MSCAI; on behalf of THE PERT Consortium®

The Search for the Holy Grail of New PE Devices

A review of interventional thrombolytic and catheter-based therapies for PE treatment.

By Mahir Elder, MD, FACC, FSCAI, and Terry Bowers, MD, FACC, FSCAI

New Insights Into the Mechanisms of Thrombosis Formation: A Focus on Inflammation

A discussion of the genetic mechanisms, role of intermediary metabolism, complex relationship between inflammation and thrombosis, and future targets for thrombus resolution.

By Scott J. Cameron, MD, PhD, and Victor F. Tapson, MD