Acandis' Acclino 1.9-F Stent System Approved in Europe for Neurovascular Interventions

August 21, 2012—Acandis GmbH & Co. KG (Pforzheim, Germany) announced the first-in-man use of its Acclino 1.9-F stent system, which received CE Mark approval in July. The company advised that the low-profile device is designed for use in neurovascular interventions as an adjunctive product in treating intracranial aneurysms with coils. It is offered as a complete set for use with the Acandis 1.9-F microcatheter. 

Acandis plans to launch the Acclino system in Europe and other CE Mark countries during the third quarter of 2012. The company stated that the Acclino system supplements Acandis' existing Neuro Closed stent system, which features a 0.027-inch delivery system for aneurysm treatment, and the Aperio thrombectomy system for treating acute ischemic stroke. 

According to Acandis, the Acclino 1.9-F stent system is available in sizes that are compatible with vessel diameters of 2 to 4 mm and is suitable for all of the cerebral main vessels, as well as vessels that are more distal and difficult to reach. The nitinol stent serves as a scaffold for the coils. The stent's closed-cell design provides conformability, even in curved segments, and provides true vessel reconstruction at the neck of the aneurysm.

Additionally, the device is designed for safe, accurate delivery. It is recapturable and repositionable at up to 90% of its deployed length and has radiopaque transport wire markers for positioning and gold markers at the stent ends for visualization. Coils can be delivered by navigating the Acandis 1.9-F low-profile microcatheter (with an inner lumen of 0.0165 inches) through the stent struts into the aneurysm, which eliminates the need for catheter exchange. The low-profile concept allows aneurysm treatment by the “jailing technique,” the company stated.

Prof. René Chapot, MD, performed the first procedures utilizing the new stent system. Prof. Chapot is Head of the Neuroradiology Department at Alfried Krupp Hospital in Essen, Germany. In the company press release, he commented, “I appreciate how easily the new 1.9-F microcatheter tracked through tortuous anatomy. This system makes it very straightforward to position the stent accurately, as there is very low friction during delivery and minimal stent foreshortening. Downsizing of the delivery systems for intracranial self-expanding stents is a key point to increase safety of endovascular procedures. This has been brightly achieved with the Acclino stent that can be used with the smallest available microcatheters for coil delivery.”