Codman's Revive SE Neurovascular Thrombectomy Device Introduced in Europe

May 5, 2011—Codman & Shurtleff, Inc., a Johnson & Johnson company (Raynham, MA) announced the European introduction of a the Revive SE blood clot retrieval and removal device, which is designed to remove blood clots and restore blood flow to the brain in the treatment of ischemic stroke patients. The device is a self-expanding nitinol basket that provides a temporary bypass across the occlusion in the brain. It can also be used for the nonsurgical removal of emboli and thrombi and be used with aspiration.

According to the company, the Revive SE is inserted with a microcatheter across the occlusion or beyond its distal edge, at which point it is deployed and expands into the vessel. It can be redeployed multiple times based on the severity of the clot. The device features a closed distal end to help prevent portions of the clot from moving further upstream within the vessel. The basket engages the clot for effective removal, is reconstrainable to ease retrieval, and is designed for optimal centering within the vessel lumen during deployment and retrieval.

“This device is an important new option because it may provide advantages over currently available treatments,” commented Martin Bendszus, MD. “Patients treated with neurothrombectomy devices such as Revive SE may achieve rapid recanalization, enhanced efficacy in treating larger vessel occlusions, and thus have an improved clinical outcome.”

“Every stroke is different, and we are now exploring the use of imaging to determine which patients may benefit most from treatment with Revive SE,” added Dr. Bendszus, who is an investigator for RIVER I (Reperfuse Ischemic Vessels with Endovascular Recanalization), a recently initiated, single-arm study in Germany that will include patient screening with magnetic resonance imaging before treatment with Revive SE.

The company received CE Mark approval for the Revive SE in February 2011. The device is not approved for distribution in the United States, the company advised.

Codman noted that in late 2010, Johnson & Johnson acquired Micrus Endovascular Corporation (San Jose, CA), which now operates under Codman Neurovascular. Through its Codman Neurovascular business unit, Codman has recently introduced the Neuroscout steerable guidewire and the Xtrasoft Orbit Galaxy coil globally, as well as the Enterprise vascular reconstruction device and delivery system in Japan for the treatment of wide-necked intracranial aneurysms.