Penumbra Introduces Red 72 Silver Label Large-Bore Reperfusion Catheter

April 24, 2025—Penumbra recently announced the introduction of the Red 72 Silver Label large-bore reperfusion catheter with SendIt technology. The device is an update of the company’s flagship Red 72 device.

Penumbra stated that the new Red 72 Silver Label is adapted from the company’s Red 43 and Red 62 catheters, which are designed to support more distal vessels.

As outlined in Penumbra’s press release, Red 72 Silver Label has a 0.072-inch (1.83-mm) lumen, an 0.085-inch (2.16-mm) outer diameter, and a 132-cm length to reach target vessels.

Additionally, the company noted that Red 72 was designed to occupy approximately 72% to 77% of the average M1 segment of the middle cerebral artery, which is within the optimal catheter-to-vessel inner-diameter ratio to create a pressure differential necessary for an effective thrombectomy procedure.

Penumbra’s SendIt technology is intended to minimize the ledge effect, simplify preparation, and ease delivery in large vessel occlusion. It features a smooth 1.5-cm taper for ease of navigation and close clot proximity.

The Red 72 Silver Label, which has been developed for speed and ease of navigation, has shown a 50% increase in trackability versus the original Red 72 with SendIt technology, stated Penumbra.

“I had the opportunity to try the new Red 72 Silver Label during a recent procedure,” commented Daniel Vela Duarte, MD, in the company’s press release. “The change and overall performance are radically better.” Dr. Vela Duarte is a neurointerventionalist with the Palm Beach Neuroscience Institute in West Palm Beach, Florida.

After completing the first case with the catheter, Ian Kaminsky, MD, an interventional neuroradiologist in Englewood, Colorado, stated, “Red 72 Silver Label tracked with ease to an M1 occlusion in a patient in their 90s with extreme cervical carotid tortuosity and underlying atherosclerotic disease. We are really looking forward to implementing this incredible technology into our practice.”