Surmodics Begins Full Commercial Release of Pounce XL Thrombectomy System

April 3, 2025—Surmodics, Inc. announced the full commercial release of the Pounce XL thrombectomy system. Pounce XL is intended for the endovascular removal of acute and chronic thrombi and emboli from peripheral arteries ranging from 5.5 to 10 mm in diameter—sizes typical of iliac and femoral arteries, noted the company.

According to Surmodics, the Pounce XL complements the company’s Pounce system and Pounce LP low-profile system, which are intended for use in 3.5- to 6-mm and 2- to 4-mm peripheral arteries, respectively. The company stated that the combined vessel diameter range of the Pounce platform provides a solution for the rapid removal of peripheral arterial thrombi and emboli throughout the lower and upper extremities.

The company advised that the Pounce XL device has been in limited-market release since January 2025. Anna Marjan, MD, a vascular surgeon at Allina Health Mercy Hospital in Coon Rapids, Minnesota, was one of the users of the Pounce XL during this initial period.

“Removing organized clot from large peripheral arteries without a surgical cutdown can be very challenging,” commented Dr. Marjan in the company’s press release. “In our first use of the Pounce XL thrombectomy system, we were able to extract a large amount of acute and subacute clot from the infrarenal aorta and common iliac arteries in a severely ischemic patient with just three passes of the device.

“Avoiding surgical cutdown reduces the need for general anesthesia and reduces risk of surgical-site infection, which benefits patients. The Pounce thrombectomy platform is my first-line, go-to solution for endovascular thrombectomy in peripheral arteries.”

The company announced FDA 510(k) clearance of Pounce XL on October 1, 2024.

On February 3, 2025, findings from the early clinical use of Pounce XL in the limited market release were announced along with early results from the PROWL registry that were presented at LINC 2025, the Leipzig Interventional Course held January 28-30 in Leipzig, Germany. PROWL is an open-label, retrospective, multicenter, United States registry of the Pounce thrombectomy platform.