Transit Scientific Closes Funding to Support XO Score and XO Cross Devices

February 3, 2021—Transit Scientific announced the close of its Series A financing round, which was led by a large multinational investor and joined by previous seed investors. Transit Scientific is a privately held company that achieved FDA clearances and multicenter, multiuser, safe-patient-use of its XO Score percutaneous transluminal angioplasty (PTA) scoring-cutting platform and the separate XO Cross 0.014- and 0.035-inch microcatheter platform in 2020.

According to the company, the XO Score sheath converts regular angioplasty balloons into vessel prep scoring and cutting systems. The device is indicated for the treatment of peripheral vascular stenosis including hemodialysis fistulas and grafts.

The XO Score features 22 individual scoring and cutting struts rotate 90° to score and cut upon balloon inflation and then rotate 90° back upon balloon deflation to facilitate balloon rewrap. The technology also allows for infusion at the site of treatment.

Transit Scientific’s XO Cross is a nontapered exoskeleton-based microcatheter technology designed to improve torque response, trackability, and control.

“XO Score successfully dilated multiple lesions that were resistant to standard or high-pressure balloon angioplasty during our first patient uses in hemodialysis fistulas,” stated Jeffrey Hoggard MD, in the company announcement. “It was particularly beneficial to be able to deploy the XO Score device with a standard PTA balloon in the juxta-anastomotic position and dilate the lesion at low and controlled inflation pressure.” Dr. Hoggard is from Raleigh Access Center in Raleigh, North Carolina.

Richard Saxon, MD, of the Tri-City Medical Center in Oceanside, California, added, “The XO Cross 014, 018, and 035 microcatheter platform adds new torque, pushability, and catheter control. We have used an 0.014-inch XO Cross to redirect the guidewire intraluminally while crossing a tibial artery [chronic total occlusion]. This would have been very difficult to achieve with other available technology.”